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newly diagnosed - methotrexate. Options
Snow Angel
#1 Posted : Monday, January 11, 2010 4:00:05 PM Quote
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Hi there,

Im 31 and newly diagnosed. my pain started in aug with very painful ball of both feet and has since progressed to my hands and every other joint in my body. i am on methotrexate, predisolone and diclofenac. also supplements of folic acid and vit d and calcium. would welcome any help and advise on taking methotrexate please. seen private consultant 3 times, now been referred with same consultant on nhs and have date in feb to see him. having blood tests every 2 weeks to check on me as taking methotrexate. would welcome any help.

many thanks

jenni.
Damned76
#2 Posted : Monday, January 11, 2010 4:13:17 PM Quote
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Hi Jenni,

Sorry that you have RA. I have been taking Methotrexate for 3 years now and it has made a big difference. I was fine for a year on just metho but now have another DMARD and naproxyn (which is an anti inflammatory like diclofenac). Hopefully when the Metho kicks in, you will be able to drop the prednisolone. How long have you been on it for?

I tend to take the Metho in the afternoon and luckily don't suffer any nausea as long as I don't get too hungry. I have them with something stodgy like a sandwich and have regular snacks until supper time. The only thing I wondered is if you are taking any kind of stomach protector. I know that a lot of us on Metho and/or anti inflammatories take omeperazole or somthing similar to help with side effects on the stomach. It's worth thinking about if the tablets do affect your stomach. I don't have any other side effects and my regular blood tests have come back fine so far. Hope it works out for you as well. Let us know how you get on.

Julie

JulieM
#3 Posted : Monday, January 11, 2010 4:41:55 PM Quote
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Hi Jenni and welcome to the forum!

I take my MTX in much the same way as Julie does. I also drink a full cup of water with and take it after my evening meal. I then nibble at regular intervals and try and concentrate on other stuff.

Eventually the space between having bloods done gets longer and longer. I only go every two months now.
YES I'VE CHANGED, PAIN DOES THAT TO PEOPLE.
jeanb
#4 Posted : Monday, January 11, 2010 5:10:39 PM Quote
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Hi Jenni

Welcome to the forum but sorry to hear you have RA

I take mtx and hydroxychloroquine (what a mouthful!). The mtx was a wonder drug for me and within about 5 months of starting it, my pain levels were down to bearable. I tend to take mine after the evening meal, with a full glass of water. I think Julie is right - do ask your GP for a stomach protector to stop any nausea.

What dose are you on at the moment? Is your consultant putting it up in stages?

I know how scary it all is at first, bu hang on in there. None of us like taking these strong drugs - I still hate it after 3 years, but they DO stop bone/joint deterioration and give us our lives back, so not taking them isn't an option.

Let us know how you get on

Love Jeanxxxx
Blue Star
#5 Posted : Monday, January 11, 2010 5:10:58 PM Quote
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Hi Jenni welcome to the forum i am Sophie 35, i cant help with the methotrexate advice as i was only on it 6 months a couple of years ago, it did not agree with me so had to come off it , there loads on here who can help im sure x
dorat
#6 Posted : Monday, January 11, 2010 6:32:14 PM Quote
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Hi Jenni,

Welcome to the forum, where you'll get lots of friendly support and information.
I take mtx and humira. Like others I take the mtx just before my evening meal, with lots of water.
I only have blood tests done every 3 months now.
Looking forward to getting to know you.

Doreen xx
smith-j
#7 Posted : Monday, January 11, 2010 7:04:20 PM Quote
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Jenni

Welcome to the forum but sorry you have the dreaded RA. I am 46 and was diagnosed in March last year and I am on Methotrexate. Leflumonide, Prednisole, Naproxen and the list goes on. Do you take a stomach protector? It is a must and I take Omeprazole which seems to be working o.k. You cannot take at the same time as the Prednisolone but I take the Omeprazole in the morning and the Prednisolone in the evening. Up until very recently I took the Methotrexate in the morning and then felt very rough all day. I was not given any advice on when to take it. However after reading a recent post on this forum I have changed it to taking it with my evening meal and feel fine (possibly because I am asleep whilst it is doing its worst).

Just a word of warning, the Methotrexate may take a while to work (it took at least 3 months before I started to feel any benefit) so don't feel despondent if it takes a while.

I hope that you start to feel better soon and keep posting as you will find invaluable advice and support on this forum. There is always someone to help you as they have kindly helped me since my diagnosis.

Jackie
xx
barbara-o
#8 Posted : Monday, January 11, 2010 7:17:30 PM Quote
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Hi Jenni,

A big warm welcome to the forum. I'm 50 and not had RA for long, I had a brief experience of taking MTX and couldn't take it for long because of problems with my liver. However, I'm sure that you'll receive excellent advise from friends on the forum and hope that you'll begin to feel better soon.

Love,

Barbara
XXXXXX
benmaise
#9 Posted : Monday, January 11, 2010 8:15:00 PM Quote
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Hello Jenny . I have an injection of metetrexate every week 20mg and two hydroxyclhoroquine a day. I think these work really well for me. I was very ill and in great pain when mine started . Its lovely to go swimming again and get about without the pain. It took a few months to work ! Hope it works well for you . Kathleen Mc. x
Kathleen_C
#10 Posted : Monday, January 11, 2010 9:57:16 PM Quote
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Hi Jenny,

A very warm welcome to the forum though I`m sorry you`ve been diagnosed with RA. It takes a while to come to terms with evrything.

I took MTX as my second drug, after sulphasalazine, and like most others I took it with/after my evening meal so that if there was any nausea I slept off the worst of it. It didn`t really work for me, so I moved on to something else, but I hope it works for you.

Take care,

Kathleen x

Calmwater22
#11 Posted : Monday, January 11, 2010 10:08:29 PM Quote
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Welcome Jenni s

Yes i did same went private for 1 st apointment,im 38 mine started age 17 ive been on Methotrexate since febuary 2008 started slowly 10mg upto 20mg now at 15mg.
u say your on steriods (predisalone)and methotrexate and nsaid(naprosyn).
you should been given a stomach protector such as Omprezole to help side effects on tummy from those.
all best for your 1st nhs appointment.
t care lv inky07
cuddly cats make my world seem so much more fun
rheumatoidymummy
#12 Posted : Tuesday, January 12, 2010 8:58:19 AM Quote
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Hi Jenni, welcome to the forum but sorry you have RA. I'm Julie and I'm 33 - I was diagnosed about 18 months ago just after the birth of my second child. I'm on a similar drug cocktail to you - MTX, Pred, Diclo. Folic Acid, Iron and Vit C. I started taking Methotrexate a year ago and am now up to 20mg - my Rheum assures me that it is probably working even though the dose has had to be steadily increased, apparently it's to do with 'young 'uns' (his word!!) metabolising the3 drug more quickly!

I take my MTX on Friday night after I've eaten, that way I sleep through the worst of the side effects and my other half is around to helpwith the little ones if I do feel unwell on Saturday. I find I need to make sure I get a good nights sleep on the night I take MTX or I do tend to feel unwell the next day which is strange!
Albert47
#13 Posted : Tuesday, January 12, 2010 1:00:05 PM Quote
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Hello Jenni

A warm to the forum, I am Albert, 62 But I am awaiting to see if I can be put on Methatrexate,I am courently on the Anti-TNF Infliximab,Azathioprine,Diclofenac and daily folic acid and steroids (prednisolone). Sorry I can't advise you but you will get good advice on here.

Take care, keep warm

Albertxxx
jenni_b
#14 Posted : Tuesday, January 12, 2010 2:52:56 PM Quote
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Hi Jenni (classy nameWink )

sorry to hear you are having some troubles on the MTX but the others have given great advice. I am 33. Have had RA since I was about 20.

Oh my word! realised i am going to be 34 this month!!!


ANyway- looking forward to getting to know you on here.

Jenni xx
how to be a velvet bulldoser
hen
#15 Posted : Tuesday, January 12, 2010 4:47:41 PM Quote
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Hi Jenni,

welcome to the forum.
I am 45 and have had RA for 20years. I am currently on Enbrel. I took MTX for many years without side effects, it worked better for me in combination with cyclosporin. It does take a few months to kick in properly. Folic acid helps minimise any nausea. The mtx began to make me really nauseous despite swapping to injections so I am currently on a break from it.

look forward to getting to know you
Diane x
amanda_lewin
#16 Posted : Tuesday, January 12, 2010 10:48:45 PM Quote
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Hi Jenni,

I have had RA since I was 8 and a half and am now MUCH older...LOL late 30s! and I can honestly say that it doesn't get easier accepting one has to take drugs like MTX, however please know that it will help you very much (after a few months), is the no1 med used for RA nowadays and very well and closely monitored.

All this assured me and I had two very good years on mtx, some are on it for decades with no problem.

Love,

Amanda
chockers
#17 Posted : Tuesday, January 12, 2010 11:36:05 PM Quote
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hi Jenni
Been on MTX 2 HALF YEARS NOW took 12 weeks to kick in i was in a right old state like a really old lady .
its been a wonder drug now moblie and running about .
i need an increase because i may have P.A ? or both or one i also have scleroderma overlap and other silly things but mtx was a wonder drug for me .

christine
The chocolate eating housewife ...The washer woman .....naughty lady
Snow Angel
#18 Posted : Wednesday, January 13, 2010 11:35:22 AM Quote
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Thankyou everyone that is really helpful, i really appreciate all your comments and advice :) xxx
Snow Angel
#19 Posted : Wednesday, January 13, 2010 11:55:59 AM Quote
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changed my name to snow angel if you were confused!! its still me :) x
Maria_R
#20 Posted : Wednesday, January 13, 2010 6:57:12 PM Quote
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Hi Jenni- and a big welcome fom me too.

I'm 52Sad and had RA for 2 years- had ups and downs but generally not too bad. It all started with pain in one of my fingers- came on suddenly and I can still remember where I was at the time (weird!) It gradually spread to wrist, elbows, shoulder then knees over about 4 months.I'm on Sulfasalzine which has been fine for 18 months - seems to be losing its effect a bit and doc told me I might have to go on Methotrexate if I get any worse. I also take diclofenac as needed, which helps a lot and paracetamol for pain relief. I went through a phase of bad fatigue but this has improved since taking folic acid.

I'll be honest and say that I've struggled at times I still can't get used to having to pace myself and take things easier.
Before I was dignosed I could hardly walk or dress myself/ do hair/ makeup/ have a bath and at one point I thought I'd never be able to do anything again. Gradually, things came back and I'm almost back to my old self for most of the time. I'm getting used to the pain and try to accept it as part of my life.

Frequent blood tests are the norm at first.-I now have them every 3 months, and see the consutant every 6.

This forum is great- so much advice, support, good fun and a big shoulder to cry on when needed. It's great to share with someone who understands.

Take care- and look after yourself!
Maria x
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